Evaluation of nanorobots for targeted delivery into the retina

2020

Conference Paper

pf

A major challenge in the treatment of eye diseases in general and retinal diseases in particular, is to deliver drugs to their target sites. Traditional intravitreal injection is based on random, passive diffusion of molecules. In order to specifically address certain structures of the retina, the use of novel particles from biomaterial research promises a more targeted application. The major challenge for such particles is the narrow macromolecular matrix of ocular tissue (including the vitreous body), which acts as a barrier and prevents the penetration of particles. Novel nanorobots from material research - more precisely: nanopropellers - that can be actively controlled through the vitreous body to reach the retina present a chance to reach desired targets in the retina.

@conference{2020Schnichels,
  title = {Evaluation of nanorobots for targeted delivery into the retina},
  author = {Schnichels, S. and Goyal, R. and Hurst, F. and Ziemsen, F. and Qiu, T. and Fischer, P.},
  volume = {61},
  pages = {1355},
  month = jun,
  year = {2020},
  doi = {},
  month_numeric = {6}
}